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动物甲状腺肿的发生与氟中毒的相关性(英文) 预览

How is Goiter Related to Fluorosis in Domestic Animals?
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摘要 氟中毒和甲状腺肿是世界范围内的两种严重的地方性疾病。研究表明,人和动物甲状腺肿大的发生与氟中毒有显著的相关性。氟化物是诱发甲状腺肿大的因素之一,在世界上某些地区这两种疾病经常重叠发生。本文综述了环境中氟过量与甲状腺肿的关系以及甲状腺肿发生的机理研究进展,以期为氟化物的毒理学,甲状腺肿的病因学以及甲状腺肿的防治提供有意义的参考。 Fluorosis and goiter are serious endemic diseases worldwide.Findings have shown that fluorosis is significantly and positively correlated with goiter between human beings and domestic animals.Previous studies indicated that fluoride was to be one of the pathogenic factors of goiter and the diseases usually overlap in the same geographic areas.In the present paper,some mechanisms of goiter associated with high levels of fluoride in the environment are summarized.Clarifying the relationship between the two diseases may provide valuable references for fluorosis and the etiology of goiter,as well as prevention and treatment of goiter.
作者 刘国艳 刘春燕 柴春彦 LIU Guo-yan;LIU Chun-yan;CHAI Chun-yan;School of Agriculture & Biology,Shanghai Jiaotong University;Key Lab of Shanghai Veterinary Biotech;
出处 《上海交通大学学报:农业科学版》 2014年第6期86-91,共6页 Journal of Shanghai Jiaotong University(Agricultural Science)
基金 国家自然科学基金(30671544)
关键词 氟中毒 甲状腺肿 拮抗 血管内皮细胞生长因子 一氧化氮 Fluorosis goiter antagonism vascular endothelial growth factor nitric oxide
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